Children’s Health

Scientists investigating heart failure have been limited to studying diseased heart tissue in the lab — understandably, as people don’t tend to pluck out a healthy heart for the sake of research. But now, scientists with access to unusable, yet still healthy, donor hearts have been able to investigate the genomic pillars behind the transition
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While the measles vaccine has eliminated the virus in many high-income countries, the global burden of disease persists with an estimated 245,000 measles cases and 68,000 measles-associated deaths worldwide in 2016. India alone accounted for 50 percent of measles cases and 30 percent of measles deaths in 2016. Although low- and middle-income countries (LMICs) account
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The U.S. Food and Drug Administration today expanded the indication for Symdeko (a combination of tezacaftor/ivacaftor) tablets for treatment of pediatric patients ages 6 years and older with cystic fibrosis who have certain genetic mutations. Last year, the FDA approved Symdeko to treat patients ages 12 and older who had the same specific genetic mutations.
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Obesity rates among pre-schoolers who receive government food aid are in decline, according to data extracted from a US nutrition program. The findings, which were published in the Journal of the American Medical Association in June 2019, confirm that previous data showing that declining obesity rates were not anomalies. Rawpixel | Shutterstock “Prevalence of childhood
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Jun 20 2019 Researchers at Boston Medical Center initiated a statewide quality improvement imitative to increase mothers’ ability to produce and provide milk for very low birth weight infants at their discharge, as well reduce the racial/ethnic disparities in milk production and provision to these infants. A new study, published June 18th in Pediatrics, indicates
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Scientists used a gene editing method called CRISPR/Cas9 to generate mice that faithfully mimic a fatal respiratory disorder in newborn infants that turns their lips and skin blue. The new laboratory model allowed researchers to pinpoint the ailment’s cause and develop a potential and desperately needed nanoparticle-based treatment. Mostly untreatable, Alveolar Capillary Dysplasia with Misalignment
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Cleveland Clinic has successfully performed its first in utero fetal surgery to repair a spina bifida birth defect in a nearly 23-week-old fetus. A multispecialty team of clinicians performed the surgery in February, and the baby, a girl, was later delivered by cesarean section near full term June 3, making it northern Ohio’s first surgery
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The U.S. Food and Drug Administration today approved Victoza (liraglutide) injection for treatment of pediatric patients 10 years or older with type 2 diabetes. Victoza is the first non-insulin drug approved to treat type 2 diabetes in pediatric patients since metformin was approved for pediatric use in 2000. Victoza has been approved to treat adult
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A new study from the University of Pittsburgh and UPMC Children’s Hospital of Pittsburgh finds that an antibody in breastmilk is necessary to prevent necrotizing enterocolitis (NEC)- an often deadly bacterial disease of the intestine- in preterm infants. Immunoglobulin A (IgA) antibodies bind to bacteria in the gut, and, according to the study, the more
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Chemicals produced by healthy bacteria could be used to assess the health of the gut microbiome and help identify critically-ill children at greatest risk of organ failure, a study published in Critical Care Medicine has found. The gut microbiome is a trillions-strong community of healthy bacteria that live inside us. They make important contributions to
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Scientists have discovered that the rotavirus vaccine reduces the likelihood of children being diagnosed with type 1 diabetes. Rotavirus causes a severe gastrointestinal illness characterized by diarrhea and dehydration. It is rarely fatal in developed countries but can be deathly in low-income countries. Kateryna Kon | Shutterstock The authors of the current study looked at
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Multiple sclerosis is a progressive disease that can severely damage nerves throughout the body. Symptoms tend to worsen, and as the disease progresses, it can cause impaired speech and motor skills. Multiple sclerosis (MS) can lead to significant difficulties in performing daily tasks and can greatly affect a person’s quality of life. There is no
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As California lawmakers attempt to tighten the rules on childhood vaccinations, they’re getting pushback from unexpected quarters: high-profile officials who support vaccines. In the past few weeks, Democratic Gov. Gavin Newsom and the members of the Medical Board of California have questioned a bill that would give the California Department of Public Health authority to
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In the first study of its kind, LSU Health New Orleans researchers report that women’s pre-pregnancy overweight or obesity produces changes in breast milk, which can affect infant growth. The research findings are published in PLOS ONE, available online here. The importance of this study is that it demonstrates that breast milk contents can vary
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